Recent study, published in Journal Science discovered that sleeping is actually good for Alzheimer’s disease and other neurological diseases. Researchers from University of Rochester Medical Center (URMC) found that waste is able to be flushed away from brain during sleeping.
Accumulation of toxin protein, amyloid-beta causes Alzheimer’s disease. In fact, the amyloid protein is also associated to other neurodegerative diseases. Study discovered that the glymphatic system (brain method to remove waste products) is highly active during sleep. In addition, brain’s cells are reduced in size and allow the waste to be removed. Through the experiment in mice, researchers found that glymphatic system was increase 10-fold more active during sleep. It was significantly remove the amyloid-beta.
Another finding was that the brain cells “shrink” about 60% during sleeping phase. This increases the spaces between cells and allow cerebral spinal fluid (CSF) to circulate more freely through brain tissue. On the other hand, the brain’s cells are closed to each other and restrict the fluid flow.
Study also discovered that hormone, noradrenaline is less active during sleep phase. Noradrenaline is normally released when brain need to be alert during stress or fear condition. They suggested that noradrenaline may control the contraction and expansion of brain’s cells during sleep. Ultimately, it increase the CSF flow.
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